Who Botox for migraine is for
Botox (onabotulinumtoxinA) is approved for chronic migraine, which has a specific definition. To qualify, you need to have:
- 15 or more headache days a month, at least 8 of which have migraine features such as throbbing pain, nausea, or sensitivity to light and sound.
- For 3 months or longer. Episodic migraine, with fewer headache days, is treated differently.
- Tried and not done well on 2 to 3 preventive medications, such as topiramate, propranolol, amitriptyline or a similar drug. Insurers require this before they approve Botox, and so does good practice.
If you meet those criteria, Botox is one of the best-studied preventive options available. It does not stop a migraine that has already started, and it does not work for everyone. In the approval trials, patients on Botox had several fewer headache days a month than those on placebo. Results vary.
How the treatment works
Dr. Scheim uses the PREEMPT protocol, the injection pattern used in the approval studies. It involves 31 small injections spread across 7 muscle areas of the forehead, temples, back of the head, neck and upper shoulders. Each injection is shallow and quick. Most patients describe it as a series of small pinches, and the whole procedure takes about 15 to 20 minutes. You can drive yourself home and go back to your day.
Injections are repeated every 12 weeks. That interval matters: Botox wears off gradually, and stretching the gap usually means the headaches return before the next cycle.
One thing we tell every patient: do not judge Botox on the first cycle. Some people notice a difference within a few weeks, but the full benefit often arrives after the second or third round of injections.
Keep a headache diary
A headache diary is not optional with Botox. It is how you and the doctor know whether it is working, and it is what the insurance company asks for at reauthorization. Every two cycles, the insurer reviews your headache days and asks whether they have fallen. Without a diary, that review becomes guesswork and coverage can lapse. A simple notebook or a phone app is fine: the date, headache yes or no, how severe, and any medication taken.
Does insurance cover Botox for migraines? Yes, when the chronic migraine criteria above are met, and every payer requires prior authorization first. That includes Medicare, Medicare Advantage and all commercial plans. Our front desk submits the request with your headache history and the preventives you have tried. Approval usually takes 7 to 10 business days, and your injection appointment is scheduled once it comes through. Patients with commercial insurance may also qualify for the manufacturer savings program, which can reduce the out-of-pocket cost of the medication, and we help you apply. Read more about insurance and self-pay.
What to expect
- Consultation. The neurologist confirms the diagnosis of chronic migraine, reviews the preventives you have tried and rules out other causes of headache. Bring any headache records and your medication history.
- Prior authorization. We submit the paperwork and let you know when it is approved.
- First injection cycle. About 15 to 20 minutes at either clinic. No sedation, no downtime.
- Diary and follow-up. You track headache days. Your next cycle is booked at 12 weeks, and the doctor reviews your diary at each visit.
- Reauthorization. Every two cycles we send your diary data to the insurer to keep coverage going.
Side effects and safety
Side effects are generally mild. The most common are neck soreness or stiffness for a few days, and temporary weakness in the injected muscles, which some patients notice as a heavy feeling in the neck or shoulders. Rarely, an eyelid can droop for a few weeks if the medication spreads from the forehead injections; this resolves on its own. Serious reactions are very uncommon. Tell the doctor if you have a neuromuscular condition, are pregnant, or have had a reaction to any botulinum toxin product.
This is not cosmetic Botox. The doses, injection sites and purpose are different, and it is prescribed and billed as a medical treatment for a neurological condition.
How many injections are there?
31, following the PREEMPT protocol, spread across 7 muscle areas of the head, neck and shoulders. It sounds like a lot, but each one is tiny and the whole set takes about 15 to 20 minutes.
How soon will I notice a difference?
Some patients notice fewer or milder headaches within two to four weeks of the first cycle. For many, the full effect builds over the second and third cycles, which is why we ask you to commit to at least three rounds before deciding whether it works for you.
Can I keep taking my other migraine medication?
Yes. Botox is a preventive, and you can still use your rescue medication for attacks that break through. The neurologist reviews your preventive medications at each visit and may reduce them as the Botox takes hold.
Which clinic offers Botox for migraine?
Both. Dr. Scheim performs the injections at Davie for Broward County patients and at Boynton Beach for Palm Beach County patients. The front desk schedules you at the clinic closest to you once your authorization is approved.
What if my insurance denies it?
Denials usually come from missing documentation, most often the record of preventives tried. We gather what is missing and appeal. If it is still not approved, the neurologist discusses other preventive options, including nerve blocks.

